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management neurology differential hematology lupus sle treatment oncology primary sclerosis syndromes systemic vasculitis amyotrophic arterial autoimmune bee behcet biliary cerebritis
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear Visual or auditory symptoms in conjunction
Visual or auditory symptoms ... conjunction with symptoms ... is important, as ... early diagnosis ... Systemic lupus erythematosus
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
systemic lupus erythematosus ... (SLE) Signs / ... #Pathophysiology ... #Diagnosis #Signs ... #Symptoms
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... , PRES Pathophysiology ... (for secondary APS ... #rheumatology #
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
(AQP4-lgG disease ... Systemic lupus erythematosus ... Manifestations #diagnosis ... #neurology #symptoms ... #signs
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... : • Pathophysiology ... #TLS #diagnosis ... #management #hematology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Demyelinating syndromes ... pain (20%) Renal disease ... SLE #systemic #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... failure PBC Signs ... and Symptoms: ... disease progresses ... #workup #hepatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
meningitis), MCC CNS symptoms ... Medium and large also ... ) Differential Diagnosis ... #signs #symptoms ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
aneurysms can also ... lupus erythematosus ... Presentation - Systemic Symptoms ... purpura: strong sign ... #rheumatology #
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... Presentation: - Disease ... course of the disease ... fasciculations Common Symptoms ... Lateral #Sclerosis #neurology
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