17 results
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
with thiazide diuretic ... • Unexplained hypokalemia ... (renal potassium ... Surreptitious diuretic ... #diagnosis #nephrology
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Hypokalemia - Differential ... Diagnosis Algorithm ... • Refeeding syndrome ... • Discontinued diuretic ... #Algorithm #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
loop or thiazide diuretics ... pressure: Active diuretic ... use, Bartter syndrome ... , Gitelman syndrome ... #nephrology #differential
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Diagnosis Algorithm ... Loop and thiazide diuretics ... @priti899 #Hypokalemia ... #nephrology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Hypokalemia Evaluation ... evaluating hypokalemia ... , Diuretics, Bartter ... #diagnosis #Algorithm ... #nephrology #low
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Algorithm Hypovolemia ... losses, Diuretic ... , Osmotic diuresis ... Stress, Drugs, Syndrome ... #nephrology
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
Thiazide or loop diuretics ... diuretic effect ... Severe Cushing syndrome ... Thiazide or loop diuretics ... #nephrology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
with hypokalemia ... Cl - Loop diuretics ... , Thiazide diuretics ... #hypokalemia ... #diagnosis #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
disequilibrium syndrome ... and nephrotic syndrome ... and nephrotic syndrome ... disease • Liddle syndrome ... #Diuresis #Nephrology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
- Compartment syndrome ... Neuroleptic malignant syndrome ... or compartment syndrome ... Loop diuretics for ... #nephrology