768 results
Systemic Sclerosis Associated Autoantibodies
Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis
Anti-centromere: Limited skin disease (~93-95%), Pulmonary
(anti-Sc170): Diffuse ... polymerase III: Diffuse ... Autoantibodies #diagnosis #rheumatology
Systemic Sclerosis (Scleroderma)
Limited - CREST:
 • Calcinosis
 • Raynaud phenomenon
 • Esophageal dysmotility
 • Sclerodactyly
 •
Telangiectasia Diffuse ... signs #symptoms #rheumatology
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
• Nucleolar: Diffuse ... ANA #patterns #rheumatology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
and knees • Diffuse ... sclerosis (DcSSc; diffuse ... Scleroderma #SSc #rheumatology
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
• Class IV - Diffuse ... glomeruli) Diffuse ... treatment #management #rheumatology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
- Scleroderma (Diffuse ... diagnosis #table #rheumatology
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
Lupus Myopathy • Diffuse ... diagnosis #comparison #rheumatology
Bronchiectasis - Permanent dilation of an airway
WHAT CAN YOU SEE ON CT?
1) Lack of tapering of
lobe of lung) 2) Diffuse ... Obstruction 6) Rheumatologic
Hemoptysis - Differential Diagnosis Framework
Massive Hemoptysis: >150-300 mL in 24h
Airway disease: 
 • Bronchitis, Bronchiectasis, Malignancy
Kaposi's sarcoma • Rheumatologic ... Vascular: • Diffuse
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
disproportionately narrowed and diffuse ... diagnosis #msk #rheumatology