22 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... and risk-stratification ... only curative treatment ... #Management #treatment ... #hematology #oncology
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients)
Important notes:
 • No
• No bleeding risk ... validated for VTE treatment ... #Scores #Calculators ... Anticoagulation #Factors #Hematology ... #Diagnosis
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
: ARDS Berlin Criteria ... : 33% • Treatment ... : No • Treatment ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis)
Major criteria 
 1. Abrupt onset of tender
Diagnostic Criteria ... for Sweet Syndrome ... Excellent response to treatment ... neutrophils #Sweet #Syndrome ... #Diagnosis #Hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Attempt if high risk ... #management #hematology ... #oncology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
) • Classify severity ... Treatment - Acute ... that ↑ bleeding risk ... #Management #treatment ... #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... Histopathologic criteria ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Irritable Bowel Syndrome (IBS) - Diagnosis and Management Summary
Diagnosis:
 • Use a positive diagnostic strategy with
Irritable Bowel Syndrome ... • Rome IV Criteria ... Treatment: • Global ... cardiovascular risk ... Irritable #Bowel #Syndrome
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
- Yamaguchi criteria ... a sore throat, ... Treatment - Mild ... : NSAIDS Treatment ... #rheumatology #
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... chemotherapy for low-risk ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management