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Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
- TTE/liver fxn? ... rhabdo/TLS) Causes ... Urinary tract obstruction ... #Nephrology #Diagnosis ... #Algorithm #Causes
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
Kidney Injury (AKI ... PROBLEM ~80% of AKI ... you confirmed diagnosis ... LorinskyMD #AKI ... simplified #workup #diagnosis
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Kidney Injury (AKI ... - Differential Diagnosis ... Artery Stenosis, Abdominal ... Post-Renal: • Obstruction ... #nephrology #causes
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
cardiorenal syndrome) • Liver ... tubular necrosis (causes ... prolonged prerenal AKI ... EricsMedicalLectures/ #AKI ... Classification #diagnosis
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... - Differential Diagnosis ... Pigments Tubular Obstruction ... ) Post-Renal (Obstruction ... #Differential #Diagnosis
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Causes of Severe ... Acute Liver Injury ... Acute biliary obstruction ... - Drug-Induced liver ... Differential #Hepatology #Diagnosis
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... Diagnosis Hepatocellular ... Acute biliary obstruction ... #Differential #Diagnosis ... #Causes #Acute
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
and Differential Diagnosis ... osmolarity If cause ... hypovolaemia and obstruction ... renal biopsy • Abdominal ... #nephrology #causes
Acute Kidney Injury - Differential Diagnosis Framework
PRERENAL:
 - Intrarenal vasoconstriction-hemodynamically mediated
 - Systemic vasodilation
 - Volume
- Differential Diagnosis ... treating underlying cause ... POSTRENAL: - Obstruction ... Manaqement: Relief of obstruction ... Kidney #Injury #AKI
Causes of Portal Hypertension According to Site of Vascular Obstruction
1) Prehepatic pre-sinusoidal: Portal vein thrombosis due
Causes of Portal ... Site of Vascular Obstruction ... to cirrhosis, Abdominal ... Cirrhosis, Polycystic liver ... #differential #diagnosis