17 results
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
the peripheral blood ... thrombocytopenic purpura/hemolytic ... uremic syndrome ... thrombocytopenia, Hematology ... #Diagnosis #Differential
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
) Low MCV - <80fL ... disease, Acute blood ... Myelodysplastic syndrome ... #differential # ... diagnosis #causes #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... : Acute blood loss ... , Acute hemolysis ... Kawasaki, Nephrotic syndrome ... Diagnosis #Algorithm #hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Drug-associated, PCH, Evans Syndrome ... - Peripheral Blood ... #Differential # ... Diagnosis #hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... Myelodysplastic syndrome ... uremic syndrome ... key #diagnosis #differential ... #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... DIC/TTP/HUS - Hemolytic ... • HCV, HBV Not ... #Diagnosis #hematology ... #nonpalpable #dermatology
Iron Deficiency Anemia - Differential Diagnosis Algorithm

Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR

 • Blood loss:
Deficiency Anemia - Differential ... TSAT, sTfR • Blood ... extravascular) hemolysis ... Gastrectomy, WHDA syndrome ... Algorithm #ferritin #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Corpuscular Volume (MCV ... ) - Differential ... Algorithm Normal Blood ... Myelodysplastic Syndromes ... Algorithm #Causes #Hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Immunoglobulin M (IgM) • Blood ... younger pts) Differential ... sensitize red blood ... #anemia #hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... • Febrile Non-Hemolytic ... in 100,000,000, HCV ... Transfusion #diagnosis #management ... #hematology #reactions