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differential management algorithm lupus abnormal coagulation prolonged sle disorders druginduced erythematosus oncology pt summary systemic anemia cerebritis classification cns comparison
How to Evaluate an Abnormal APTT Step 1: Is the PT or APTT Artifactually Prolonged? Step 2: Is
to identify the cause ... of Prolonged APTT ... ISN Education ... #prolonged #diagnosis ... #hematology #evaluation
Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
- Differential Diagnosis ... /uL Initial Workup ... iron studies, PT/aPTT ... #Algorithm #hematology ... #workup
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Hemolysis - Diagnostic ... Algorithm and Causes ... Increased red cell production ... #Workup #Hematology ... #Diagnosis *
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... #Algorithm #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... : INR/PT, aPTT(liver ... #Causes #Workup ... #hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... the PT and the aPTT ... synthesis (impaired production ... #diagnosis #differential ... #hematology #coagulation
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... allergy, drug reaction ... glucocorticoid treatment ... #Differential #diagnosis ... #hematology #eosinophilia
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Pre-analytical cause ... synthesis - Impaired production ... #diagnosis #differential ... #hematology #coagulation
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
coagulation factors - Reduction ... INR < 2.3 - APTT ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
established disease) • aPTT ... mixing study (aPTT ... normal in mild cases ... #Management #treatment ... #hematology
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