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HepatoRenal Syndrome - Pathophysiology

Dr. Edgar V. Lerma @edgarvlermamd - Nephrology Secrets https://amzn.to/34t5DgJ

#HRS #HepatoRenal #Syndrome #Pathophysiology #Diagnosis
HepatoRenal Syndrome ... - Pathophysiology ... amzn.to/34t5DgJ #HRS ... #HepatoRenal #Syndrome ... #AKI
Hepatorenal Syndrome (HRS) - Diagnostic Criteria
HRS-AKI (Acute: previously known as HRS Type 1)
 • ↑ Creatinine
Hepatorenal Syndrome ... Criteria HRS-AKI ... renal ultrasound HRS-NAKI ... 2) • HRS-AKD ... #Hepatorenal #Syndrome
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
failure (a.k.a. hepatorenal ... syndrome) Intrarenal ... vasculitis - TTP/HUS ... tubular necrosis (causes ... Classification #diagnosis #nephrology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... Hypoperfusion • Hepatorenal ... syndromes • Drugs ... Ethylene glycol) TTP/HUS ... #Nephrology #Differential
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
Common causes of ... calcineurin inhibitors, hepatorenal ... syndrome) • Vascular ... #causes #Acute ... Differential #Diagnosis #nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... Distributive Shock, HRS ... Abdominal Compartment Syndrome ... Differential #Diagnosis #nephrology ... #causes #algorithm
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... osmolarity If cause ... pressure • TTP / HUS ... Differential #Diagnosis #nephrology ... #causes
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
- Summary Acute ... Epidemiology: • 1-2 cases ... Guillain-Barre Pathophysiology ... Albuminocytologic dissociation ... variants: (1) acute
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... (GBS) Acute autoimmune ... Incidence: 1 to 2 cases ... albuminocytologic dissociation ... the underlying pathophysiology