32 results
Symptoms Distinguishing Groups of Cutaneous Drug Reactions
IgE-mediated reactions:
 • Onset minutes to hours into treatment course
to hours into treatment ... Raised off of the skin ... Onset days into treatment ... Blistering and/or skin ... #dermatology #clinical
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
 - Inflammatory
Vesiculobullous Skin ... Bullous impetigo - Reaction ... diabeticorum) - Reaction ... Vesiculobullous #SkinRash #dermatology ... Diagnosis #Algorithm #causes
Causes of Pseudocellulitis - Differential Diagnosis Framework for Cellulitis Mimics

Cellulitis: Deep skin and subcutaneous fat infection

Pseudo
Causes of Pseudocellulitis ... Cellulitis: Deep skin ... avoid allergic reactions ... Pseudocellulitis: • Drug reaction ... #dermatology #skin
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... eosinophilia (common causes ... allergy, drug reaction ... glucocorticoid treatment ... symptoms (eg, skin
Approach to the Rash in a an oncology patient - MINT-C Mnemonic
M - Malignancy: Leukemia cutis,
Gangrenosum, NEH T - Treatment ... Cutaneous Adverse Reactions ... dermatoses #skin ... MINTC #Mnemonic #dermatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
characterized by extensive skin ... Edema in 70% of cases ... Skin involvement ... disease: symptomatic treatment ... DRESS #Syndrome #dermatology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Treatment
Stop offending agents:
 • List as allergies
Drug Reaction with ... DRESS) Syndrome Treatment ... , IVIG etc • Skin ... DRESS #Syndrome #Treatment ... #Management #dermatology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... • Secondary Causes ... fever • Drug reactions ... Differential #Diagnosis #hematology ... #nonpalpable #dermatology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
- Transfusion Reactions ... without other cause ... : 33% • Treatment ... : No • Treatment ... #hematology #diagnosis
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... TRALI): Leading cause ... more likely to cause ... infections with skin ... diagnosis #management #hematology