14 results
An Approach to Jaundice Workup Algorithm by CBC and LFT Pattern

- Dr. Eric Strong @DrEricStrong

#Jaundice #Workup
Algorithm by CBC and ... LFT Pattern - ... Workup #Algorithm #Patterns ... #LFTs #Diagnosis ... #Hepatology #Differential
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Smith, Sm/RNP, Scl ... -7, PL-12, MDA5, ... ARUPConsult @ARUPLabs #ANA ... #differential # ... diagnosis #rheumatology
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... #LFTs #Hepatocellular ... Transaminitis #diagnosis ... #differential # ... hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... Diagnosis Algorithm ... • Cirrhosis (any ... • Others #LFTs
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Function Tests - Differential ... Diagnosis Algorithm ... Hepatocellular Pattern ... Others, Cirrhosis (any ... Burak @kwburak #LFTs
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Diagnosis Algorithm ... elliptocytosis - RBC Enzyme ... Cold AIHA • PCH ... #Diagnosis #Algorithm ... #Causes #Hematology
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
Smith, Sm/RNP, Scl ... • Fibrillarin, RNA ... ARUPConsult @ARUPLabs #ANA ... #differential # ... diagnosis #rheumatology
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
evaluation of the pattern ... the magnitude of enzyme ... #LFTs #Abnormal ... #Liver #Enzymes ... #Differential #
Inflammatory Myopathies
Dermatomyositis
 • Onset: Subacute
 • Pattern: Proximal
 • CK: Up to 50X ULN
 • Autoantibodies:
: Proximal and distal ... Inflammatory #Myopathies #differential ... #diagnosis #comparison ... #rheumatology # ... table
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... Source of Liver Enzyme ... liver #chemistry #diagnosis ... #differential # ... #LFTs #RValue #