34 results
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... ) occur in high ... malignancies Treatments ... #Tumor #Lysis #Syndrome ... TLS #oncology #management
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Initial screening test ... severe disease Treatment ... Severe disease- high ... Summary #diagnosis #rheumatology ... #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
immature blasts and high ... Spontaneous if high ... hydration - Hyperkalemia ... TLS #diagnosis #management ... #hematology
Hyperkalemia - Management Algorithm
 • IV calcium
 • IV insulin and glucose and/or salbutamolt
 • Consider
Hyperkalemia - Management ... with narrow base, best ... #potassium #high ... #diagnosis #management ... #algorithm #treatment
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
and Management ... tourniquet / IVF line draw ... Cortisol+ACTH stim test ... #Treatment #potassium ... #nephrology #K
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Induction Rx: high-dose ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis #management
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Framework and Management ... - Compartment syndrome ... Differential #Diagnosis #Management ... #causes #treatment ... #nephrology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... Arthritis, AS Treatment ... exacerbations: high-dose ... #diagnosis #management ... signs #symptoms #rheumatology
The rationale for aggressive treatment of generalized status epilepticus was described previously here.  In short,
for aggressive treatment ... In short, best outcomes ... cause aspiration, hyperkalemia ... #Management #Neurology
Renal Cell Carcinoma (RCC) - Diagnosis and Management Summary
Clinical features - Classic triad (flank pain, hematuria,
Diagnosis and Management ... Budd Chiari syndrome ... disease Imaging and Treatment ... Hypercalcemia 4 ... RCC #Diagnosis #Management