31 results
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Initial screening test ... block • Sjogren syndrome ... polymyositis overlap syndrome ... severe disease Treatment ... Summary #diagnosis #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Meningitis, Myelopathy, Encephalopathy ... Puncture, EEG Treatment ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
reactions, Drug-associated ... , PCH, Evans Syndrome ... Laboratory Tests ... Differential #Diagnosis #hematology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Necrotizing myopathy is associated ... anti-synthetase syndrome ... after 2 years of treatment ... Myositis #diagnosis #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Systemic disease associated ... skin injury) • Neurologic ... is a skin prick test ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
Proposed treatment algorithm for antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis

#anca #vasculitis #treatment #algorithm #rheumatology #nephrology
Proposed treatment ... antibody (ANCA)-associated ... anca #vasculitis #treatment ... #algorithm #rheumatology ... #nephrology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... Liver function tests ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Associated with: ... thyroid, Sjogren syndrome ... Bedside: ice pack test ... /Edrophonium test ... diagnosis #management #neurology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... associated with ... • Bicytopenia Treatment ... diagnosis #management #treatment ... #hematology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Posterior Reversible Encephalopathy ... may precede the neurologic ... fluctuations PRES-Associated ... epilepticus Treatment ... #management #neurology