15 results
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
of Clinical Significance ... - Differential Diagnosis ... #Gammopathy #Clinical ... #Differential #Diagnosis ... #hematology #oncology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... disease (SVC/IVC occlusion ... Behcet syndrome (Clinical ... refractory disease : monoclonal ... signs #symptoms #rheumatology
Diagnosis of Cryoglobulinemia Vasculitis

1) Presence of cryoglobulin 
Circulating immunoglobulins that precipitate with cold temperature and dissolve
not related to clinical ... arterioles) MONOCLONAL ... l) : Vascular occlusion ... arthritis • Renal ... #Rheumatology #
Behcet's Syndrome - Diagnosis
Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease):
 • Recurrent,
vasculitis - Skin ... test Most Common Clinical ... Wide variety of skin ... (e.g. uveitis, retinal ... #criteria #rheumatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
pulmonary emboli, and ocular ... thrombi including retinal ... : • + Clinical ... #rheumatology # ... hematology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Alpha & Mu) Skin ... thrombosis+Pulm HTN+skin ... , retinal, DVT, ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... Syndrome: - Ocular ... Differential Diagnosis ... reactions, and vaso-occlusive ... #rheumatology #
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... : • A clinical ... sites such as the collar ... SAPHO #Syndrome #Rheumatology ... #Dermatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
- Differential Diagnosis ... pulmonary and renal ... Vasculitis Differential Diagnosis ... reactions, and vaso-occlusive ... #Rheumatology
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS)
Fracture, Osteoporosis
 - Increased osteoclast activity and bone resorption
Complications of Monoclonal ... ; vaccinations Renal ... rituximab (in clinical ... Complications #diagnosis ... #hematology