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management rheumatology differential dermatology causes hepatology neurology algorithm lupus systemic erythematosus oncology pain classification joint signs skin summary workup acute
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Dermatomyositis Anti-LKM (liver ... La) - Sjogren's syndrome ... Goodpasture's syndrome ... #diagnosis #table ... #rheumatology #
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
GI - Felty syndrome ... • Felty's syndrome ... , Behçet's syndrome ... #differential #diagnosis ... #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
syndromes Clinical ... erythematosus [SLE ... ALT ↑ bilirubin level ... Treatment: • Corticosteroids ... #Diagnosis #Management
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Malar rash • SLE ... • Rheumatic fever ... IBD • RA • SLE ... Antiphospholipid-antibody syndrome ... #differential #diagnosis
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
block • Sjogren syndrome ... polymyositis overlap syndrome ... Treatment: • ... #Summary #diagnosis ... #rheumatology #
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... Splenomegaly - CTD (SLE ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... Associated - SLE
Causes of Knee Effusions - Differential Diagnosis Framework Knee Effusion Red Flags: 1. Fever/Chills/Joint pain/Night sweats/Weight loss - DDX: -
- Differential Diagnosis ... arthritis - SLE ... Effusions: - Hematologic ... #differential #diagnosis ... #msk #physicalexam
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
- Differential Diagnosis ... Trauma: Shock liver ... Metabolic: Wilson Disease ... Singh @rav7ks See ... #causes #hepatology
Shock - Differential Diagnosis Framework - MAP <65. SBP <90, drop in SBP > 40 -
- Differential Diagnosis ... SBP <90, drop in ... Insufficiency, Liver ... , Severe Valve Disease ... Abdominal compartment syndrome
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Abnormality • SLE ... discoloration) • Liver ... • Nephrotic syndrome ... Systemic #Secondary #dermatology ... #Differential #Diagnosis
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