7 results
Causes of Peripheral Weakness without Sensory Changes - Differential Diagnosis Algorithm
No Objective Weakness
 • Cardio-pulmonary disease
Hyperreflexia • Lead toxicity ... Polymyositis • Duchenne ... Muscular Dystrophy ... • Statin Toxicity
Amiodarone Toxicity and Monitoring

Tremor Ataxia 
Ocular neuritis 
Corneal Microdeposits 
Bradycardia 
Pulmonary fibrosis 
Hepatotoxicity 
Blue-gray skin
Amiodarone Toxicity ... Distribution - Half ... #Amiodarone #Toxicity ... Diagnosis #Management #Pharmacology
Cardiomyopathies 

Manifestations of cardiomyopathy (CM) range from microscopic alterations in cardiac myocytes to fulminant Heart Failure
Glycogen storage) • Toxicity ... Duchenne-Becker ... dystrophy, Neurofibromatosis
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
– elimination half-life ... #Toxicology #Toxicity ... #Diagnosis #Pharmacology
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
ICU due to short half-life ... glycol (solvent) toxicity ... No pharmacologic ... (Haldol) - No pharmacologic
Toxic Alcohol Ingestion: Methanol
Solvent found in cleaning and printing solutions, adhesives, stains, paint removers,
antifreeze agent in
gasoline additive Pharmacology ... minutes, elimination half-life ... formic acid) causes toxicity
Digoxin Pharmacology and Monitoring

 • Digoxin’s half-life is 30-45 hours in healthy adults
 • When monitoring
Digoxin Pharmacology ... • Digoxin’s half-life ... Kat_Watson #Digoxin #Pharmacology ... toxicology #management #toxicity