22 results
Lactic Acidosis Classification - Type A vs Type B
Type A Lactic Acidosis: Sepsis, Ischemic bowel, Hemorrhagic
Lactic Acidosis Classification ... Acidosis: Sepsis ... bowel, Hemorrhagic shock ... Hypoperfusion, Cardiogenic shock ... Short bowel (D-lactate
SEPSIS AND SEPTIC SHOCK

DEFINITION AND PATHOPHYSIOLOGY
 • Sepsis: Life-threatening organ dysfunction due to a dysregulated host
Life-threatening organ dysfunction ... • Septic shock ... = 65 mm Hg and lactate ... with Shock: Sepsis ... #Septic #Shock
Causes, classification and compensatory responses to shock.

Shock can be caused by any pathological process that leads
Causes, classification ... vasodilatation, myocardial dysfunction ... distributive (septic ... Differential #Causes #Types ... #Classification
Shock Classification and Differential Diagnosis
SHOCK
 • MAP <65, SBP <90, drop in SBP > 40
 •
Shock Classification ... malperfusion • Lactate ... / Low SVR • Sepsis ... #Classification ... Differential #Diagnosis #Types
Systemic Inflammatory Response Syndrome (SIRS)
•	Non-specific (infections vs non-infectious)
•	≥2 of the following:
o	Temp >38°C or <36°C
o	HR >90 bpm
o	RR
• Organ dysfunction ... hypoperfusion/organ dysfunction ... Septic Shock • ... o Lactate >2 mmol ... #sirs #shock #lactate
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
undifferentiated shock ... is in impending shock ... /hypoxemia/Sepsis ... syndrome - Sepsis ... #typeb #classification
Shock Types and Classification
DISTRIBUTIVE 66%
 • Sepsis/SIRS, anaphylaxis, adrenal insufficiency, liver failure, toxins, spinal/neurogenic
 • Warm
Shock Types and ... Classification ... DISTRIBUTIVE 66% • Sepsis ... Cold and Dry #Shock ... #Types #Classification
Intraoperative Sepsis - Guidelines for Crises in Anaesthesia

Severe sepsis (hypotension persisting after initial fluid challenge of
30ml.kg-1 or blood lactate ... shock (sepsis with ... end organ dysfunction ... including blood gas, lactate ... Check serial lactates
Lactic Acidosis - Differential Diagnosis Framework

Type A: Impaired O2 Delivery (DO2)
 • Decreased O2 Delivery: Hypotension
Cardiogenic & Septic ... Shock, Severe Anemia ... Microcirculatory dysfunction ... Mitochondrial dysfunction ... Malaria, Late Sepsis
Lactic Acidosis - Classification and Differential Diagnosis
Type A Lactic Acidosis: Inadequate Oxygen Delivery
 • Anaerobic muscular
Lactic Acidosis - Classification ... hypoperfusion, Shock ... Fructose, Isoniazid, Lactate-based ... Lactic #Acidosis #Classification ... #TypeB #lactate