9 results
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
Sulfonylureas - Pharmacology ... Mechanisms of Action ... contraindicated in CKD ... #Summary #DM2 # ... diabetes #endocrinology
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... Diuretic Sites of Action ... ) Loop agents (eg ... Diuretics #Sites #Action ... #nephrology #pharmacology
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... Mechanisms of Action ... side effects (e.g ... #Summary #DM2 # ... diabetes #endocrinology
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
SGLT2 Inhibitors - Pharmacology ... Mechanisms of Action ... GU infections (e.g ... #Summary #DM2 # ... diabetes #endocrinology
Impact and Challenges With Vitamin D to Treat Secondary Hyperparathyroidism in Patients With Chronic Kidney Disease
Ergocalciferol (D2 ... patients with CKD ... - Biologically active ... - Biologically active ... #Pharmacology #
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
Receptor Agonists - Pharmacology ... Mechanisms of Action ... side effects (e.g ... #Summary #DM2 # ... diabetes #endocrinology
Estimating the Total Daily Dose (TDD) of Insulin: Weight-Based Dosing
TDD in units of insulin = N
(stage IV or V CKD ... as Basal (Long-acting ... Weight #Based #pharmacology ... #endocrinology ... #diabetes #DM2
Pruritus Treatment Algorithm for Hemodialysis Patients 

Non-PharmacoIogicaI Measures 
 • Use gentle soap e.g. Dove
Pruritus Treatment Algorithm ... moisturizing cream (NOT lotion ... Pruritus #Treatment #Algorithm ... Uremia #Management #Nephrology ... #CKD
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
transfusions), ↓insulin (DM ... heparinized tube) • ECG ... VBG (acidosis), CK ... (10g PO tid) - caution ... Treatment #potassium #nephrology