37 results
Cutaneous Manifestations of Monoclonal Gammopathy
 • Extravascular lg Deposits: Systemic amyloidosis, Nodular amyloidosis, Macroglobulinoderma, Follicular hyperkeratotic
Cutaneous Manifestations ... Extravascular lg Deposits: Systemic ... monoclonal #gammopathy #Cutaneous ... manifestations #dermatology ... #skin #clinical
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Treatment
Stop offending agents:
 • List as allergies
Eosinophilia and Systemic ... Symptoms (DRESS) Syndrome ... cyclosporine, IVIG etc ... • Skin: topical ... Treatment #Management #dermatology
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Gammopathy of Clinical ... Differential Diagnosis Neurologic-Centered ... nemaline myopathy Cutaneous-centered ... leak syndrome ( ... Differential #Diagnosis #hematology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
associated with systemic ... Most common extra cutaneous ... Causes: - Idiopathic ... , breast CA - Hematologic ... #diagnosis #dermatology
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Disorders secondary to Systemic ... halt nail growth (e.g ... • Nephrotic syndrome ... #Secondary #dermatology ... Diagnosis #Algorithm #causes
Primary Dermatological Lesions
Primary lesions are physical changes in the skin considered to be caused directly by
considered to be caused ... altered colour e.g ... nipple-like mass e.g ... . e.g. psoriasis ... #Diagnosis #Dermatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... Fever is the main clinical ... underlying disease (eg ... • Infection (eg ... Diagnosis #Management #Hematology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... - Purpura - Skin ... : • Clinical triad ... Henoch-Schönlein purpura) • Cutaneous ... tissue disorder (e.g
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Alpha & Mu) Skin ... gangrenosum • Cutaneous ... et diutinum Neurologic ... thrombosis+Pulm HTN+skin ... Paraproteinemias #Hematology
Pisa Syndrome (pleurothotonus) on Physical Exam
A tonic flexion of the trunk of the body to one
Caused commonly ... by: - drugs (e.g ... neurodegenerative disorders (eg ... #PhysicalExam #clinical ... #neurology #posture