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diagnosis differential management secondary signs symptoms alice arteritis bleeding bruising cerebritis chronic dermatology dili druginduced enlarged erythematosus fatigue gca giantcell
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
• Thrombus (e.g ... Myeloproliferative disorders ... (eg. polycythemia ... Inflammatory • Systemic ... #Causes #Hematology
Alice in Wonderland Syndrome What? Metamorphophsia - Distortions of the visual perceptions with changes in size (micro
• CNS: parietal ... lobe • Retina • Systemic ... • Infection (e.g ... Brain lesions (e.g ... • Psychiatric disorders
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Differential Diagnosis Algorithm ... Sequestration Disordered ... Rare • Drugs (e.g ... #Causes #Hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... of Systemic Lupus ... autoantibodies that will cause ... Lumbar Puncture, EEG ... #neurology #rheumatology
Causes of Tremors - Movement Disorders - Differential Diagnosis Algorithm Action Tremor - Occurs During Voluntary Muscle
Causes of Tremors ... - Movement Disorders ... Cerebellar Disease (e.g ... palsy • Multiple System ... MovementDisorders #Neurology
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... halt nail growth (e.g ... #Secondary #dermatology ... Differential #Diagnosis #Algorithm ... #causes
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... Neoplastic / Hematologic ... Pulmonary Disease Neurologic ... • Drug Abuse (e.g ... • Somatization Disorder
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
brainstem syndromes (e.g ... AQP4-lgG disease; e.g ... pain • Extra-CNS ... Comorbid autoimmune disorders ... (Systemic lupus
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
of information (e.g ... for alternative causes ... Hepatic vascular disorder ... (e.g. ascites), ... #hepatology
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Non-neuromuscular disorder ... Cardiac, pulmonary etc ... ) • CNS -> PNS ... electromyographic (EMG ... Differential #Diagnosis #neurology
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