29 results
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
distinction has HUGE treatment ... and first-line treatment ... thrombocytopenia #Comparison ... #Diagnosis #Table ... #Hematology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
#management #algorithm ... #pharmacology #treatment ... #medications #table ... decisionaid #cardiology #hematology ... #warfarin #dosing
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Malabsorption (e.g ... warfarin, DOACs (e.g ... Deficiencies #Summary #table ... #comparison #diagnosis ... #hematology #deficiency
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
sequestration and activation ... : 33% • Treatment ... Transfusion #Reactions #hematology ... #diagnosis #comparison ... #table
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Willebrand Syndrome - Diagnosis ... and Management ... vonWillebrand #Syndrome #Diagnosis ... #Management #treatment ... #hematology #differential
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 ... IFN-y) → Excessive activation ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
and Management ... hemophilia type (e.g ... Chronic Management ... #Management #treatment ... #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
uncovered incidentally during ... glucocorticoid treatment ... signs or symptoms (eg ... #Differential #diagnosis ... #hematology #eosinophilia
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
excessive macrophage activation ... Diagnosis via genetic ... • Bicytopenia Treatment ... #management #treatment ... #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
permeability Diagnosis ... Lumbar Puncture, EEG ... Treatment: ... CNS #neurology #rheumatology ... #management #treatment