19 results
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... Most cases diagnosed ... membrane into the CNS ... mineralization Symptoms ... respiratory failure • Neurologic
CNS Infections - Viral Encephalitis and Bacterial Meningitis - Differential Diagnosis Framework

Viral Encephalitis:
MCC: Enteroviruses (e.g., coxsackievirus
Enteroviruses (e.g ... Coltivirus Symptoms ... • Common clinical ... influenzae Symptoms ... #neurology #meningitis
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
decades of life Causes ... and clinical associations ... and duration of symptoms ... #rheumatology # ... comparison #table
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... autoantibodies that will cause ... permeability Diagnosis ... Lumbar Puncture, EEG ... #neurology #rheumatology
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
Non-inflammatory Causes ... nervous system (CNS ... MRI lesions and clinical ... consistent with MS ... BEE #Syndromes #neurology
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... involvement: Intractable nausea ... pain • Extra-CNS ... Manifestations #diagnosis ... #neurology #symptoms
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
without other cause ... ARDS to explain symptoms ... Transfusion #Reactions #hematology ... #diagnosis #comparison ... #table
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... renal failure Clinical ... are not caused ... (e.g. incidental ... anterior/posterior MSK
Differentiating NBTE from Infective Endocarditis
No pathognomonic signs/symptoms or echo features that are specific to NBTE, and
pathognomonic signs/symptoms ... high index of clinical ... in up to 30% of cases ... #Endocarditis #comparison ... #table
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Discontinuation of causal ... druginduced #lupus #sle #comparison ... #table #rheumatology ... #diagnosis #management