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An Approach to Jaundice - Differential Diagnosis

- Increased Production (Prehepatic)
- Decreased Clearance (Intrahepatic + Posthepatic)

Dr. Eric
An Approach to Jaundice ... - Differential Diagnosis ... #Differential #Table ... #Causes #Intrahepatic ... #Hepatology #bilirubinemia
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
Jaundice - Differential ... Diagnosis Algorithm ... Sepsis • Drugs (e.g ... #Algorithm #Causes ... #Hepatology #bilirubinemia
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
Acute sickle cell hepatic ... onset RUQ pain, jaundice ... Supportive with blood ... Hepatobiliary #hepatology ... #differential #diagnosis
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Causes of Splenomegaly ... - Differential Diagnosis ... Hepatic, Portal, ... #Differential #Diagnosis ... #Hematology
Classification of Jaundice
Unconjugated hyperbilirubinemia (predominantly indirect bilirubin)
 • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Classification of ... Jaundice Unconjugated ... , hepatitis, hepatic ... #Classification ... #diagnosis #conjugated
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Medications - Heparin ... • Acute DIC - Septic ... Deficiencies #Summary #table ... #comparison #diagnosis ... #hematology #deficiency
Deciphering the SAAG - Serum to Ascites Albumin Gradient
Ascites is either made in the liver sinusoid
albumin in the blood ... albumin to escape blood ... , Pancreatitis etc ... Matherly @liverprof #Diagnosis ... #Hepatology #SAAG
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... for alternative causes ... liver disease, Hepatic ... presentation: Hepatic ... #Algorithm #hepatology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
- Differential Diagnosis ... Blood Loss, Occult ... HgbE, HgbC, etc. ... #Differential #Diagnosis ... #Hematology
Shock - Differential Diagnosis by Classification

Hypovolemic (Intravascular volume depletion)
 - Hemorrhagic 
   • Trauma
- Differential Diagnosis ... by Classification ... exacerbation (any cause ... obstruction to blood ... #Table #CriticalCare