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differential causes comparison abnormal aflp algorithm aptt hellp management obstetrics pregnancy prolonged pt thrombocytopenia ttphus aclf acute atlas bleeding blood
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Summary of Coagulation ... ) • Advanced Liver ... Deficiencies #Summary #table ... #comparison #diagnosis ... #hematology #deficiency
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic Liver ... Kidney Failure Coagulation ... Failure #Cirrhosis #Hepatology ... #gastroenterology ... #management #diagnosis
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
- Differential Diagnosis ... Rare • Drugs (e.g ... Iatrogenic) • Liver ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
and Acute Fatty Liver ... presents with coagulation ... pregnancy * Severe coagulation ... AFLP #obstetrics #hematology ... #diagnosis #table
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
presents with coagulation ... pregnancy * Severe coagulation ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... to HDS, drugs, OTC ... of information (e.g ... #Injury #Diagnosis ... #Algorithm #hepatology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Chemotherapy (e.g ... disease, Etc. ... valve induced, Etc ... #differential #diagnosis ... #hematology #microscopy
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Early liver disease ... Reduced liver synthesis ... Prolonged #Causes #diagnosis ... #differential #hematology ... #coagulation
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Liver Chemistries ... • Albumin • Coagulation ... #chemistry #diagnosis ... #differential #Hepatology ... #transaminitis
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... • Reduced liver ... Prolonged #Causes #diagnosis ... #differential #hematology ... #coagulation
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