14 results
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
MYH9-Related Disorder ... structure and cell ... Defects #comparison #table ... #differential #diagnosis ... #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... function test, ANA (e.g ... not required in all ... #Diagnosis #Causes ... #Workup #hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Pregnancy - TTP/HUS, HELLP ... the critically ill ... Liver tests, Low Platelets ... AFLP #obstetrics #hematology ... #diagnosis #table
Consensus Indications for Irradiated RBC Transfusions:

Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
immunodeficiency disorders ... Hematopoietic stem cell ... HLA-selected products (e.g ... or crossmatched platelets ... #Indications #Hematology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
the critically ill ... Liver tests, Low Platelets ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... coagulation (DIC) - HELLP ... . lupus, CLL, lymphoma ... lymphoproliferative disorders ... #hematology #anemia
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Consider sickle cell ... with or without platelet ... thrombocytopenia - DIC, TTP, HELLP ... Consider RBC membrane disorder ... Algorithm #workup #hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Chemotherapy (e.g ... Liver disease, Etc ... Unstable hemoglobin disorders ... #differential #diagnosis ... #hematology #microscopy
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... to a low blood platelet ... Disorders • Nutritional ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Ascites - Diagnostic Approach and Differential Diagnosis
The most common causes: cirrhosis, malignancy and heart failure. Approx
than one cause (e.g ... carcinomatosis, HF, etc ... : 1) General appearance ... Routine tests: Cell ... #hepatology