19 results
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... . lupus, CLL, lymphoma ... lymphoproliferative disorders ... #differential #diagnosis ... #hematology #anemia
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
MYH9-Related Disorder ... structure and cell ... Defects #comparison #table ... #differential #diagnosis ... #hematology
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
and laboratory diagnosis ... non-specific red cell ... other testing (platelet ... count, D-dimer, egg ... #anemia #Hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
- Differential Diagnosis ... Myeloproliferative disorders ... Serum Sickness Hemolytic ... Disease • Sickle Cell ... Algorithm #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... Consider sickle cell ... with or without platelet ... Consider RBC membrane disorder ... Algorithm #workup #hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Chemotherapy (e.g ... Microangiopathic Hemolytic ... Unstable hemoglobin disorders ... #differential #diagnosis ... #hematology #microscopy
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... function test, ANA (e.g ... not required in all ... #Diagnosis #Causes ... #Workup #hematology
Consensus Indications for Irradiated RBC Transfusions:

Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
immunodeficiency disorders ... Hematopoietic stem cell ... HLA-selected products (e.g ... or crossmatched platelets ... #Indications #Hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
iron deficiency, hemolysis ... Chronic inflammatory disorders ... (e.g. autoimmune ... myeloid leukemia (CML ... #Causes #hematology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
defects. 1) HELLP (Hemolysis ... Liver tests, Low Platelets ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table