25 results
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
and Differential Diagnosis ... Pelger-Huet, Macrocytic anemia ... - bcr-able (+) ... #hematology #Markers ... #Differential #Diagnosis
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
of Sickle Cell ... #Diagnosis #Management ... #Hematology #SickleCell ... #Complications ... Manifestations #Workup
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Chemotherapy (e.g ... Liver disease, Etc ... Unstable hemoglobin disorders ... #differential #diagnosis ... #hematology #microscopy
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Diagnosis: • ... lymphoproliferative disorders ... • Neutropenia, anemia ... #workup #oncology ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Microangiopathic hemolytic anemia ... . lupus, CLL, lymphoma ... lymphoproliferative disorders ... #hematology #anemia
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... changes), high MCV anemia ... not required in all ... #hematology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Diagnosis: • Pancytopenia ... Consider stem cell ... neutropenic fever) Complications ... #diagnosis #management ... #treatment #hematology
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... (BM) ablative disorders ... of substrate (e.g ... #Algorithm #Diagnosis ... #Workup #Hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
malignancies • Anemia ... Chronic inflammatory disorders ... (e.g. autoimmune ... myeloid leukemia (CML ... #Causes #hematology
Consensus Indications for Irradiated RBC Transfusions:

Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
immunodeficiency disorders ... Hematopoietic stem cell ... HLA-selected products (e.g ... #Indications #Hematology ... #BloodBank #Management