33 results
Algorithm for the Evaluation and Management of Transfusion Reactions

This algorithm was developed by Dr. Eric Madden,
Evaluation and Management ... of Transfusion ... #Transfusion #Reactions ... #Algorithm #Diagnosis ... #Management #Hematology
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
Evaluation and Management ... Manifestations and Management ... #Diagnosis #Management ... #Hematology #SickleCell ... Manifestations #Workup
Consensus Indications for Irradiated RBC Transfusions:

Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
Irradiated RBC Transfusions ... Intrauterine and neonatal transfusions ... HLA-selected products (e.g ... #Indications #Hematology ... #BloodBank #Management
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Purpura (TTP) Diagnosis ... Contraindication to platelets transfusion ... Thrombocytopenic #Purpura #management ... #treatment #rheumatology ... #hematology
Thromboelastography (TEG) Based Management
 - If R time prolonged -> FFP 
 - If MA low
Thromboelastography (TEG) Based Management ... 50 -> platelet transfusions ... Thromboelastography #TEG #Management ... #treatment #diagnosis ... #hematology
Thromboelastography (TEG) based therapy and Management

If r time prolonged -> FFP
If MA low -> plts/cryoprecipitate (if
based therapy and Management ... 50 - > platelet transfusions ... Thromboelastography #TEG #Management ... #Diagnosis #Hematology
Approach to the Hypercoagulable State
Arterial thromboembolism
→ Cardiac rhythm monitoring, Echocardiogram, Vascular imaging
→ Test for APS, particularly
• Provoked (e.g ... - No other workup ... Hypercoagulable #Workup ... #hematology #diagnosis ... #algorithm #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... HUS) • Other: Transfusion ... implicated) - Transfusion ... #differential #diagnosis ... #hematology #anemia
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
TRALI vs TACO - Transfusion ... plasma volume transfusion ... #Reactions #hematology ... #diagnosis #comparison ... #table
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Symptomatic anemia Diagnosis ... Supportive care (transfusions ... Aplastic #Anemia #diagnosis ... #management #treatment ... #hematology