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differential algorithm management dermatology rheumatology syndrome blood bruising elevatedmcv macrocytosis oncology product purpura secondary thrombocytosis transfusion acronym activation arteritis atlas
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... - Differential Diagnosis ... function test, ANA (e.g ... changes), high MCV anemia ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... microangiopathy: Thrombotic thrombocytopenic ... lymphoproliferative disorders ... #hematology #anemia
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... - Differential Diagnosis ... • Rheumatic disorders ... following EtOH induced thrombocytopenia ... Iron deficiency anemia
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential Diagnosis ... Megakaryopoiesis • Aplastic Anemia ... #Algorithm #Causes ... #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... : - Thrombocytopenia ... - Hemolytic anemia ... fever • Drug reactions ... #hematology #rheumatology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... - Differential Diagnosis ... Algorithm Thrombocytopenia ... Rare • Drugs (e.g ... #Hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Chemotherapy (e.g ... Liver disease, Etc ... Unstable hemoglobin disorders ... #differential #diagnosis ... #hematology #microscopy
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... malignancies • Anemia ... Chronic inflammatory disorders ... (e.g. autoimmune ... #Causes #hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... - Differential Diagnosis ... HgbE, HgbC, etc. ... #Differential #Diagnosis ... #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... - Differential Diagnosis ... Increased Requirement (e.g ... • Small Bowel Disorder ... #Hematology
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