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management differential 4tscore algorithm blood causes heparininduced product transfusion activation anemia comparison extravascular framework hemeonc hemolysis hemolytic hemophagocytic hlh intravascular
Heparin-Induced Thrombocytopenia (HIT) Evaluation Algorithm - Dr. Josh Farkas @PulmCrit #4TScore #HITT #Algorithm #HeparinInduced #Thrombocytopenia #Diagnosis #Criteria #Hematology
Heparin-Induced Thrombocytopenia ... (HIT) Evaluation ... PulmCrit #4TScore #HITT ... #Diagnosis #Criteria ... #Hematology
4T Score for Heparin-Induced Thrombocytopenia Interpretation of the 4T score: 0-3 points: Low probability (<<1%) -
Heparin-Induced Thrombocytopenia ... further workup of HITT ... agent #4TScore #HITT ... #Diagnosis #Criteria ... #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential Diagnosis ... Quinidine • HIT ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Framework Decreased Production: - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... - Differential Diagnosis ... NSAIDs, quinine, etc ... Antibody-mediated: ITP, HITT ... #Framework #hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
- Transfusion Reactions ... Pathophysiology: 2 hit ... #Transfusion #Reactions ... #hematology #diagnosis ... #comparison #table
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... microangiopathy: Thrombotic thrombocytopenic ... Other: Transfusion reaction ... #differential #diagnosis ... #hematology #anemia
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
leukopenia, anemia, and thrombocytopenia ... Histopathologic criteria ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion Reactions ... haptoglobin, ↑LDH, etc ... purpura & severe thrombocytopenia ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
in recipient (e.g ... haptoglobin, ↑LDH, etc ... purpura & severe thrombocytopenia ... #Transfusions #diagnosis ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
is a critical diagnostic ... Cytopenias (anemia, thrombocytopenia ... Diagnostic Criteria ... of 8 HLH-2004 criteria ... #Management #Hematology
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