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diagnosis differential lupus neurology pharmacology rhabdomyolysis acidosis cerebritis classification cns crrt diuresis diuretics elevation encephalopathy erythematosus excretion hcq hydroxychloroquine hyperkalemia
Hydroxychloroquine Serum Measurement in SLE • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
Measurement in SLE ... 200ng/mL Best indications ... (e.g. renal failure ... #rheumatology # ... levels #lupus #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... autoantibodies that will cause ... #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis #management
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Diagnosis and Management ... Herpes, Coxsackie etc ... per day until stable ... #Summary #causes ... #treatment
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Etiology: • Medications ... heparinized tube) • ECG ... only if no clear cause ... Table below) ... #nephrology #K
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Framework and Management ... Summary Causes ... Herpes, Coxsackie, etc ... #causes #treatment ... #nephrology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
again we might see ... hypoxemia/Sepsis etc ... perfusion - shock->treatments ... before beginning treatment ... - HIV/HAART medications
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
irrigation • Management ... Kidney stones caused ... Tolvaptan) • Treatment ... #Pharmacology #Medications ... #Table
Renal Replacement Therapy (RRT) - ICU One Pager Summary Indications (AIEOU): • A: Acidosis (usually severe metabolic)
Pager Summary Indications ... ); see ExTRlP guidelines ... Dialyzer is rigid case ... #Therapy #RRT #managment ... #nephrology #CRRT
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Immunosuppressive agents, Renal ... Electrolyte abnormality, Medication ... • Treatment of ... Syndrome #diagnosis #management ... #neurology
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