11 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
family history - Medications ... function test, ANA (e.g ... (CVID, WAS), (neurologic ... or if a primary hematologic ... #Workup #hematology
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
200ng/mL Best indications ... • Special cases ... (e.g. renal failure ... Measurement #SLE #rheumatology ... levels #lupus #management
Consensus Indications for Irradiated RBC Transfusions:

Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
Consensus Indications ... antithymocyte globulin, etc ... HLA-selected products (e.g ... #Hematology #BloodBank ... #Management
Treatment of giant cell arteritis (GCA)

1st Line Strategy - GC 0.7 mg/kg/day, except for:
 • Aortitis
of giant cell arteritis ... MTX or TCZ in case ... GCA #Treatment #Management ... #Relapses #Indications ... #rheumatology #2ndline
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... vision changes, etc ... identifies 85 to 95% of cases ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
autoantibodies that will cause ... Lumbar Puncture, EEG ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... cerebritis #diagnosis #management
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... Discontinuation of causal ... sle #comparison #table ... #rheumatology # ... diagnosis #management
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
nonerosive inflammatory arthritis ... Rule out other causes ... Tetracyclines etc ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Etiology: • Medications ... heparinized tube) • ECG ... only if no clear cause ... Elimination (see Table ... STOP offending medications
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
onion-skinning" of arteries ... • Refractory cases ... Renal #Crisis #rheumatology ... #nephrology #diagnosis ... #management