17 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... Anaphylaxis, Acute Renal ... #diagnosis #management ... #hematology #oncology
Emergent Hyperkalemia Treatment Algorithm
ECG changes, weakness, K+ >6.5 Or renal insufficiency with K >5.5 with cellular
Emergent Hyperkalemia ... ECG changes, weakness ... , K+ >6.5 Or renal ... ) ECG changes ... #Management
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Framework and Management ... Herpes, Coxsackie, etc ... per day until stable ... Differential #Diagnosis #Management ... #causes #treatment
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Diagnosis and Management ... Herpes, Coxsackie etc ... oxidative iniury Treatment ... per day until stable ... Dialysis for severe hyperkalemia
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
post-hypothermia • ↓ Renal ... Excretion: - Renal ... heparinized tube) • ECG ... 15 suggests ↓ renal ... Elimination (see Table
Indications for Serum Protein Electrophoresis (SPEP)
 • Suspected multiple myeloma, Waldenström's macroglobulinemia, primary amyloidosis, or related
chemotherapy, etc ... associated with renal ... suspected • Hypercalcemia ... possible malignancy (e.g ... Electrophoresis #SPEP #Hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
organ damage • Treatment ... hydration - Hyperkalemia ... unless worrisome EKG ... TLS #diagnosis #management ... #hematology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
irrigation • Management ... Torsemide) • Acute pulmonary ... Hyponatremia • Hypercalcemia ... Tolvaptan) • Treatment ... #Medications #Table
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
and lower jaw Treatment ... antiinflammatory properties e.g ... Tetracyclines etc ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management
Intraoperative  Bradycardia - Guidelines for Crises in Anaesthesia
Bradycardia in theatre should not be treated as
remember to tailor treatment ... reservoir bag and APL ... known drug causes (eg ... myocardial infarction, hyperkalaemia ... Checklist #Diagnosis #Management