15 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
(Heparin) • Sodium-channel ... #hyperkalemia #differential ... #diagnosis #pathophysiology ... pharmacology #potassium #medications ... #druginduced
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... Algorithm DILI ... duration), Several medications ... non-essential drug/HDS treatments ... hepatitis #DILI #DrugInduced
Etiologies of Hypernatremia - Differential Diagnosis
GI losses / Insensible losses
Sodium Overload
Transcellular Movement of Water
Central Diabetes Insipidus
Hypernatremia - Differential ... Diagnosis GI losses ... Insensible losses Sodium ... in kidneys) - Medications ... #Diagnosis #Table
Drug Induced Kidney Injury
 • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy
 • Osmotic
@kdjhaveri #DrugInduced ... #KidneyInjury #differential ... #diagnosis #algorithm ... #nephrology #Medications
Causes of Hypernatremia - Differential Diagnosis Algorithm
Hypernatremia - Excess free water loss, Serum Sodium >145 mmol/L
High
Diagnosis Algorithm ... water loss, Serum Sodium ... Polyuria scheme) e.g ... Hypernatremia #Nephrology ... Diagnosis #Algorithm
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... : SIADH, Renal Sodium ... #Hyponatremia #differential ... #diagnosis #table ... #sodium #nephrology
Hypernatremia - Differential Diagnosis and Treatment
Hypernatremia is almost always due to unreplaced water loss (free water
Diagnosis and Treatment ... patient weight (eg ... #Diagnosis #Treatment ... #management #nephrology ... #sodium
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
INDICATIONS FOR ... glucocorticoid treatment ... signs or symptoms (eg ... #Differential # ... diagnosis #hematology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Rhabdomyolysis - Differential ... Diagnosis Framework ... Herpes, Coxsackie, etc ... per day until stable ... #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Etiology: • Medications ... heparinized tube) • ECG ... Elimination (see Table ... STOP offending medications ... #potassium #nephrology