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diagnosis causes differential management thrombocytopenia abnormal algorithm laboratory prolonged aflp cascade dic disorders disseminated hellp intravascular obstetrics pathophysiology platelet pregnancy
Algorithm for Investigation of Abnormal Coagulation Tests - Prolonged PT - Prolonged aPTT and Prolonged PT - Prolonged aPTT Dr.
Investigation of Abnormal Coagulation ... Tests - Prolonged PT ... and Prolonged PT ... #Algorithm #Coagulation ... #Laboratory #Hematology
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
Causes of Prolonged PT ... • Prolonged PT ... • Prolonged PT ... Algorithm #Causes #Hematology ... #coagulation #disorders
Coagulation Cascade Mnemonic - PITT vs PET PITT (with an I) = Intrinsic = APTT
Coagulation Cascade ... = Intrinsic = APTT ... E)= Extrinsic=PT ... @pinoygastro #Coagulation ... PET #diagnosis #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal PT ... Congenital intrinsic coagulation ... intravascular coagulation ... #differential #hematology ... #coagulation
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
for a Prolonged PT ... and aPTT If the ... PT and the aPTT ... #differential #hematology ... #coagulation
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
2B) • Normal PT ... INR • Normal aPTT ... factor VIII) Treatment ... Disease #Diagnosis #Hematology
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
Intravascular Coagulation ... platelet aggregation PT ... , aPTT: • Expected ... using INR use PT ... Scoring #diagnosis #hematology
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Summary of Coagulation ... EricsMedicalLectures/ #Coagulation ... Deficiencies #Summary #table ... #comparison #diagnosis ... #hematology #deficiency
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT ... Fibrinogen: ↓ • PT ... + Bleeding Treatment ... INR < 2.3 - APTT ... #management #hematology
Mixing Study • Clotting tests can be abnormal due to either a clotting factor deficiency, or
factor activity (e.g ... clotting test (e.g ... PT and/or aPTT) ... Study #diagnosis #hematology ... pathophysiology #hematology
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