17 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Acute hemolysis, deficiency ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Diagnosis #Algorithm #hematology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Hemophilia A - Deficiency ... Hemophilia B - Deficiency ... Deficiencies #Summary #table ... #comparison #diagnosis ... #hematology #deficiency
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
distinction has HUGE treatment ... and first-line treatment ... thrombocytopenia #Comparison ... #Diagnosis #Table ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Other: Transfusion reaction ... (usually IgG) (e.g ... - Transfusion reaction ... G6PD deficiency) ... differential #diagnosis #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
- Transfusion Reactions ... : 33% • Treatment ... : No • Treatment ... #hematology #diagnosis ... #comparison #table
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC: Pyridoxine deficiency ... Thalassemia, Iron deficiency ... B12 or Folate deficiency ... Chemotherapy (e.g ... differential #diagnosis #hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
RBC>13 • Iron Deficiency ... (Eg Causes: Chronic ... Malabsorption, Dietary Deficiency ... HgbE, HgbC, etc. ... Algorithm #Causes #Hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
allergy, drug reaction ... glucocorticoid treatment ... signs or symptoms (eg ... Differential #diagnosis #hematology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion Reactions ... haptoglobin, ↑LDH, etc ... recipients w/ IgA deficiency ... Associated Graft Versus ... diagnosis #management #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
in recipient (e.g ... haptoglobin, ↑LDH, etc ... recipients w/ IgA deficiency ... Associated Graft Versus ... diagnosis #management #hematology