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differential management algorithm syndrome abnormal aflp anemia aptt hellp obstetrics pregnancy prolonged pt reactions thrombocytopenia ttphus workup arteritis ascites bleeding
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Malabsorption (e.g ... warfarin, DOACs (e.g ... Autoimmune disorders (e.g ... #comparison #diagnosis ... #hematology #deficiency
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... - Differential Diagnosis ... Rare • Drugs (e.g ... #Algorithm #Causes ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
intravascular coagulation ... (usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... #hematology #anemia
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
presents with coagulation ... child * Severe cases ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
presents with coagulation ... child * Severe cases ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
Causes of Localized ... - Differential Diagnosis ... • Infection (e.g ... #Algorithm #Causes ... #Hematology #Oncology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
to one factor e.g ... e.g. heparin ... inhibitory drugs e.g ... #diagnosis #differential ... #hematology #coagulation
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... (e.g. heparin contamination ... inhibitory drugs (e.g ... specific inhibitor (e.g ... #hematology #coagulation
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
- Differential Diagnosis ... Iron Deficiency (Eg ... Other • e.g ... HgbE, HgbC, etc. ... #Hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Immunosuppression (e.g ... Autoimmune diseases (e.g ... Malignancies (eg ... #oncology #diagnosis ... #differential #hematology
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