11 results
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
- Vasculitis, e.g ... - Vasculitis, e.g ... Microscopic polyangiitis ... Associations #diseases #diagnosis ... #table #rheumatology
Urine Microscopy Crystals
Uric Acid crystals:
 - Formation promoted by acidic urine
 - Seen in tumor lysis
in tumor lysis syndrome ... urease-producing organisms (e.g ... acidic urine - Diagnostic ... #Crystals #comparison ... #table #urinalysis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Algorithm DILI ... of information (e.g ... non-essential drug/HDS treatments ... vascular disorder (e.g ... #Algorithm #hepatology
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
Algorithm Endocrine ... Neoplastic / Hematologic ... Pulmonary Disease Neurologic ... • Drug Abuse (e.g ... Chronic Fatigue Syndrome
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... colored compounds (e.g ... heme, bilirubin, etc ... #nephrology #interpretation ... #diagnosis
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
- Differential Diagnosis ... Algorithm Persistent ... • Fanconi's syndrome ... polyangiitis (GPA) / microscopic ... Protein deposition (eg
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Lumbar Puncture, EEG ... Treatment: ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
unit activity on EMG ... of diazepam • EMG ... EMG Studies: ... Treatment: • ... #neurology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
and lower jaw Treatment ... antiinflammatory properties e.g ... Tetracyclines etc ... diagnosis #management ... #Dermatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... not be subtle e.g ... E.g. 80 yo ESR cutoff ... vision changes, etc ... Treatment of GCA