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Algorithm for the Long-Term Treatment of Venous Thromboembolism 

Reference: https://doi.org/10.1182/blood.2019002364

by Dr. Clive Kearon and Dr. Susan
the Long-Term Treatment ... of Venous Thromboembolism ... doi.org/10.1182/blood ... #VTE #Anticoagulation ... #Algorithm #Hematology
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... Chemotherapy (e.g ... disease, McLeod blood ... Liver disease, Etc ... differential #diagnosis #hematology
Consensus Indications for Irradiated RBC Transfusions:

Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
for Irradiated RBC ... Transfusions: Cellular blood ... HLA-selected products (e.g ... #Irradiation #RBC ... #Indications #Hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
- Fe/TlBC, MCV/RBC ... Iron Deficiency (Eg ... Causes: Chronic Blood ... HgbE, HgbC, etc. ... Algorithm #Causes #Hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
ABO incompatible blood ... Shock (14%) • Thromboembolism ... + Bleeding Treatment ... hydration • RBC ... #management #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
in recipient (e.g ... Volume Reduced RBC ... • Washed RBC ... haptoglobin, ↑LDH, etc ... diagnosis #management #hematology
Longterm Venous Thromboembolism Treatment Algorithm
Treat for 3 months and reassess
 • Isolated distal DVT (without cancer)
Longterm Venous Thromboembolism ... Treatment Algorithm ... doi.org/10.1182/blood ... #management #hematology ... #anticoagulation
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
Diagnosis: On the CBC ... , RBCs & WBCs are ... Hydroxyurea + anticoagulation ... Thrombocythemia #ET #hematology ... diagnosis #management #hematology