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diagnosis management differential algorithm comparison oncology reactions rheumatology activation cerebritis coagulation dic disorders disseminated elevatedmcv eosinophil eosinophilia erythematosus hemeonc hemophagocytic
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... Blood Loss, Occult ... Secondary to Inflammation ... HgbE, HgbC, etc. ... #Hematology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
of high parity blood ... without other cause ... : 33% • Treatment ... #Reactions #hematology ... diagnosis #comparison #table
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... autoantibodies that will cause ... thrombosis and/or blood-brain ... Lumbar Puncture, EEG ... Treatment:
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... in recipient (e.g ... haptoglobin, ↑LDH, etc ... Causes purpura & ... diagnosis #management #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Peripheral blood ... • Screen for secondary ... glucocorticoid treatment ... signs or symptoms (eg ... Differential #diagnosis #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
ABO incompatible blood ... transfusion • ... Thromboembolism (7%) • CNS ... Treat primary cause ... #hematology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
hypertension and/or drug treatment ... Constitutional disorders, eg ... Megaloblastic anemia-rare ... including white blood ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... DDX: Rule Out Secondary ... Causes • Anemia ... Syndromes #diagnosis #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Classified among the secondary ... nervous system (CNS ... with leukopenia, anemia ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... -> AML: Blast crises ... - infiltrates (anemia ... bone marrow and secondary ... #Leukemia #Hematology
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