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diagnosis management differential rheumatology algorithm anemia comparison intravascular product syndrome anesthesia anesthesiology atlas basics bloodbank cerebritis checklist clinical cns coagulation
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
Reactions TRALI ... of high parity blood ... without other cause ... #Reactions #hematology ... diagnosis #comparison #table
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Blood Product Transfusions ... in recipient (e.g ... haptoglobin, ↑LDH, etc ... Causes purpura & ... diagnosis #management #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... haptoglobin, ↑LDH, etc ... Causes purpura & ... TRALI): Leading cause ... diagnosis #management #hematology
Consensus Indications for Irradiated RBC Transfusions: Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
Irradiated RBC Transfusions ... : Cellular blood ... HLA-selected products (e.g ... Irradiation #RBC #Blood ... #Hematology #BloodBank
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... reaction, Paroxysmal ... reaction • Intrinsic ... Extravascular #Causes ... differential #diagnosis #hematology
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
• Peripheral blood ... • Screen for secondary ... allergy, drug reaction ... glucocorticoid treatment ... Differential #diagnosis #hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Causes of Anemia ... Blood Loss, Occult ... 18% • Anemia Secondary ... HgbE, HgbC, etc. ... #Hematology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
hypertension and/or drug treatment ... Constitutional disorders, eg ... - Secondary autoimmune ... including white blood ... #hematology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
Treatment depends ... maintained fever CAUSES ... transfusion • ... Allergic reaction ... • Intracranial blood
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
autoantibodies that will cause ... thrombosis and/or blood-brain ... Lumbar Puncture, EEG ... Treatment: ... APS), Secondary
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