19 results
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
For most indications ... #management #algorithm ... #pharmacology #treatment ... #medications #table ... decisionaid #cardiology #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
autoantibodies that will cause ... Lumbar Puncture, EEG ... Treatment: ... cerebritis #diagnosis #management ... #treatment
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
200ng/mL Best indications ... (e.g. renal failure ... Measurement #SLE #rheumatology ... pharmacology #levels #lupus ... #management
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
life-threatening • Treatment ... Usual therapeutic management ... sle #comparison #table ... #rheumatology # ... diagnosis #management
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Testing Algorithm INDICATIONS ... for secondary causes ... glucocorticoid treatment ... signs or symptoms (eg ... Differential #diagnosis #hematology
Consensus Indications for Irradiated RBC Transfusions:

Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
Consensus Indications ... antithymocyte globulin, etc ... HLA-selected products (e.g ... #Hematology #BloodBank ... #Management
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
duration), Several medications ... , Hidden OTC and ... non-essential drug/HDS treatments ... for alternative causes ... Diagnosis #Algorithm #hepatology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Diagnosis and Management ... normal in mild cases ... hemophilia type (e.g ... Chronic Management ... #treatment #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Systemic lupus ... SJIA], systemic lupus ... Treatment: • Corticosteroids ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... organ damage • Treatment ... unless worrisome EKG ... TLS #diagnosis #management ... #hematology