15 results
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Megakaryopoiesis • Aplastic Anemia ... ITP • SLE • CLL ... Heart Valve) #Thrombocytopenia ... Algorithm #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
intravascular coagulation ... microangiopathy: Thrombotic thrombocytopenic ... . lupus, CLL, lymphoma ... differential #diagnosis #hematology ... #anemia
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Thrombocytopenia ... the critically ill ... presents with coagulation ... Obstetrics #OBGyn #Hematology ... Diagnosis #Comparison #Table
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Thrombocytopenia ... the critically ill ... presents with coagulation ... AFLP #obstetrics #hematology ... #diagnosis #table
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Chemotherapy (e.g ... Post-splenectomy, Etc ... Liver disease, Etc ... valve induced, Etc ... differential #diagnosis #hematology
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
microangiopathic hemolytic anemia ... non-specific red cell ... intravascular coagulation ... count, D-dimer, egg ... #Hematology #Pathology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Lymphocytic Leukemia (CLL ... 5) Symptoms of anemia ... or thrombocytopenia ... or thrombocytopenia ... Leukemia #oncology #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
incompetent • CLL ... • Neutropenia, anemia ... , thrombocytopenia ... microglobulin Treatment ... workup #oncology #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
function test, ANA (e.g ... changes), high MCV anemia ... not required in all ... or if a primary hematologic ... Causes #Workup #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
platelet count (thrombocytopenia ... IDUS) • Immune Thrombocytopenia ... factor (GCSF) treatments ... marrow studies Treatment ... Syndromes #diagnosis #hematology