56 results
Inherited Qualitative Platelet Defects
Bernard-Soulier Syndrome
 • Defect of adhesion due to a lack of GP Ib/IX/V
MYH9-Related Disorder ... structure and cell ... Defects #comparison #table ... #differential #diagnosis ... #hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
and Differential Diagnosis ... • Lymphoid (CLL ... - bcr-able (+) ... #hematology #Markers ... #Differential #Diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
and Platelet Disorders ... - Differential Diagnosis ... not required in all ... #Platelet #Disorders ... Causes #Workup #hematology
Thrombocytopenia - Differential Diagnosis Algorithm

Decreased production:
 • Bone marrow suppression
 • Bone marrow failure
 • Bone
Thrombocytopenia ... - Differential Diagnosis ... Connective tissue disorders ... #Algorithm #hematology ... #platelets
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
- Differential Diagnosis ... Algorithm Thrombocytopenia ... Platelet Function ... Rare • Drugs (e.g ... Algorithm #Causes #Hematology
Platelet disorders and Aggregometry
Glanzmann Thrombasthenia
 • Defective aggregation to all agonists except ristocetin
 • Normal platelet,
Platelet disorders ... aggregation to all ... Gplb receptor • Thrombcytopenia ... #disorders #hematology ... #differential #diagnosis
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
inherited bleeding disorder ... Laboratory • Normal platelet ... count (mild thrombocytopenia ... factor VIII) Treatment ... #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... inflammation • Thrombocytopenia ... #Differential #Diagnosis ... #hematology #rheumatology ... #nonpalpable #dermatology
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
distinction has HUGE treatment ... and first-line treatment ... Microangiopathy #thrombocytopenic ... #Comparison #Diagnosis ... #Table #Hematology
PLATELETS Mnemonic for Causes of Thrombocytopenia

P - Platelet Disorders (DIC, ITP, TTP)
L - Leukemia, Lymphoma
A -
for Causes of Thrombocytopenia ... Disorders (DIC, ... Mnemonic #Acronym #Thrombocytopenia ... #Differential #Diagnosis ... #Hematology