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diagnosis rheumatology management ana antinuclear erythematosus sle systemic autoantibodies classification comparison joint msk pain patterns reactions signs symptoms syndrome workup
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Associated Rheumatic Diseases ... connective tissue disease ... Juvenile Idiopathic Arthritis ... #Antinuclear #Antibodies ... #diagnosis #differential
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers to antibodies ... Using fluorescence ... ANA #patterns #rheumatology ... #diagnosis #differential
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
Origin (FUO) - Differential ... Malignancy: - Hematologic ... ): Lupus, Rheumatoid ... arthritis, Vasculitis ... (Temporal arteritis
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Aortitis - Differential ... (RA), Systemic lupus ... Sara Dong @swinndong ... #Aortitis #Differential ... #Diagnosis #rheumatology
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
RA: rheumatoid arthritis ... SLE : systemic lupus ... CTILD #Diagnosis #Differential ... #Comparison #Table ... #Pulmonary #Rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Manifestations: - Arthritis ... SLE-Related Auto-Antibodies ... (aPL) 30-45% Differential ... sclerosis, Still's disease ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... . hematologic) ... vein thrombosis Hematologic ... 1, SCL-70, RNP antibodies ... anticardiolipin antibodies
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Symptoms of Joint Disease ... categories of joint disease ... mainly or only during ... Joint #Pain #MSK #rheumatology ... approach #workup #differential
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... Association with disease ... also be measured using ... with auto-immune diseases ... #table #ANA
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... life-threatening • Treatment ... Evolution: Chronic disease ... sle #comparison #table ... #rheumatology #
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