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differential causes thrombocytopenia aflp algorithm anemia management obstetrics pregnancy ttphus coagulation defects deficiencies elevatedmcv extravascular hemolysis hemolytic inherited intravascular leukostasis
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
- Differential Diagnosis ... • Folate Deficiency ... Non-lmmune: • HELLP ... Syndrome • TTP ... Algorithm #Causes #Hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
Syndrome and Acute ... Pregnancy (AFLP) Three syndromes ... AFLP #obstetrics #hematology ... #diagnosis #table ... #comparison
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Hemophilia A - Deficiency ... Hemophilia B - Deficiency ... Deficiencies #Summary #table ... #comparison #diagnosis ... #hematology #deficiency
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
Pregnancy Three syndromes ... coagulation defects. 1) HELLP ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... coagulation (DIC) - HELLP ... syndrome - ... G6PD deficiency) ... #hematology #anemia
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Differential Diagnosis ... Increased Requirement (e.g ... • Small Bowel ... Myelodysplastic Syndromes ... Algorithm #Causes #Hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
limb ischemia, bowel ... organ damage • Treatment ... unless worrisome EKG ... #TLS #diagnosis ... #management #hematology
Inherited Qualitative Platelet Defects Bernard-Soulier Syndrome • Defect of adhesion due to a lack of GP Ib/IX/V
Bernard-Soulier Syndrome ... a storage pool deficiency ... Platelet #Defects #comparison ... #table #differential ... #diagnosis #hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
and lower jaw Treatment ... antiinflammatory properties e.g ... Tetracyclines etc ... diagnosis #management ... #Dermatology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential Diagnosis ... hypertension and/or drug treatment ... Constitutional disorders, eg ... anemia-rare - Copper deficiency-rare ... #causes #hematology
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