30 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Syndrome and Acute ... child * Severe cases ... #AFLP #obstetrics ... #hematology #diagnosis ... #table #comparison
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
Pregnancy Three syndromes ... #AFLP #Obstetrics ... #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
Causes of Thrombocytopenia ... - Differential Diagnosis ... Non-lmmune: • HELLP ... Syndrome • TTP ... #Hematology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Malabsorption (e.g ... Septic shock, Obstetric ... Deficiencies #Summary #table ... #comparison #diagnosis ... #hematology #deficiency
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... coagulation (DIC) - HELLP ... syndrome - ... #hematology #anemia
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... NSAIDs, quinine, etc ... antiphospholipid syndrome ... - Pregnancy: HELLP ... #Framework #hematology
Causes of Post-Partum Hemorrhage - Differential Diagnosis Algorithm
Blood Loss: >500mL post vaginal delivery OR >1000 mL
Causes of Post-Partum ... - Differential Diagnosis ... purpura (TTP) • HELLP ... syndrome • Disseminated ... #Obstetrics #OBGyn
A toxidrome is a syndrome (set of symptoms) caused by specific medications or toxins.

There are 5
toxidrome is a syndrome ... set of symptoms) caused ... antihistamines #Diagnosis ... Toxicology #Toxidromes #Comparison ... #Table #Anticholinergics
Fever vs Hyperthermia
Fever:
 • Regulated in the hypothalamic thermoregulatory center
 • "Set point" raised by prostaglandin
TNF-a1pha, IL-6, etc ... Neuroleptic malignant syndrome ... ; Serotonin syndrome ... #Hyperthermia #comparison ... #diagnosis #management
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
Syndrome (Hemolysis ... #obstetrics #hepatitis ... #comparison #differential ... #diagnosis #icp ... #HELLP #AFLP