11 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... (DILI) DILI Types ... Calculate R-Value ... Idiosyncratic #differential ... #Diagnosis #Management
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
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Diagnosis Algorithm ... • PCH ... Prosthetic heart valves ... #Diagnosis #Algorithm ... #Causes #Hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Diagnosis Framework ... HELLP - Grafts, Valves ... Drug-associated, PCH ... #Diagnosis #hematology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
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pattern of liver injury ... been reported (eg AIH-PBC ... , AIH diagnosis ... #Diagnosis #Management ... #Hepatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... www.ncbi.nlm.nih.gov/pmc ... to bolus these values ... liver or renal injury ... classification
Shock Types - Classification
State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
Shock Types - Classification ... or spinal cord injury ... #types #diagnosis ... #management #criticalcare ... #differential
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Agglutinin Disease 3 Types ... women • 15% of AIHA ... younger pts) Differential ... Hemoglobinuria (PCH ... hemolytic #anemia #hematology
Gustilo-Anderson Classification for Open Fractures

Antibiotic regimen for open fractures is determined by the severity of the
severity of the injury ... contamination and the type ... MH/CCF/CWRU EM ... Open #Fractures #Diagnosis ... #Management #Orthopedics
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... Antibiotics (Bactrim, PCN ... , rhabdo/crush injury ... Aldosterone, RTA Type ... IV, AI • Ureterojejunostomy
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... permanent alopecia Differential ... Diagnosis: • ANCA-associated ... Kikuchi disease • Type-I ... Hematologic: • AIHA