39 results
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Diagnosis Framework ... HELLP - Grafts, Valves ... Drug-associated, PCH ... , Evans Syndrome ... #Diagnosis #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... priapism • Lab values ... WBC >100k, + lab signs ... #TLS #diagnosis ... #management #hematology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Diagnosis Hepatocellular ... obstruction, HELLP Syndrome ... #Diagnosis #Causes ... Acute #algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Pathophysiology ... Signs and Symptoms ... Diagnosis: • ... bile ducts Differential ... #workup #hepatology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Diagnosis Algorithm ... Cold AIHA • PCH ... Prosthetic heart valves ... #Diagnosis #Algorithm ... #Causes #Hematology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
Primary Sjogren’s Syndrome ... biliary cirrhosis (PBC ... erythematosus (SLE) Signs ... #Pathophysiology ... #Diagnosis #Signs
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic ... Ill-appearing, vital sign ... Immunocompromised #Diagnosis ... #Dermatology #Rash ... Targetoid #Algorithm #Differential
Causes of Biliary Dilatation - Differential Diagnosis
 • Physiological: ↑ Age, Cholecystectomy, Opioid dependence, Post-sphincterotomy
 •
Biliary Dilatation - Differential ... Diagnosis • Physiological ... sludge), Mirizzi's syndrome ... pancreatitis, PSC ... #diagnosis #hepatology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Thrombocytosis - Differential ... Diagnosis Secondary ... Myelodysplastic syndrome ... Myelofibrosis (MF ... #hematology #secondary
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
biliary cirrhosis (PBC ... La) - Sjogren's syndrome ... Endomyseal antibody (EMA ... Associations #diseases #diagnosis ... #table #rheumatology