19 results
diagnosis management causes workup chronic classification cll hemolysis leukemia lymphocytic rheumatology abscess acidosis agglutinin algorithm apml autoimmune bandemia biliary cell
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Drug-associated, PCH ... Defects: Sickle cell anemia ... #Diagnosis #hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Biliary Cirrhosis (PBC ... ) - Summary PBC ... 30-65 years PBC ... Pathophysiology ... bile ducts Differential
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
elliptocytosis - RBC ... Cold AIHA • PCH ... immune-complex hemolytic anemia ... Prosthetic heart valves ... Algorithm #Causes #Hematology
Multiple Myeloma Diagnosis and Management Summary Clinical Signs: • hyperCalcemia 28% (bone demineralization) • Renal disease 48%
Management Summary Clinical ... demineralization) • Renal disease ... ratio >100 if FLC value ... is also >100 CMC ... Diagnosis #Management #oncology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Normal: < 1% Clinically ... • Autoimmune diseases ... appreciate the value ... #CBC #hematology ... #pathophysiology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... • Symptoms of anemia ... Blood smear - RBC ... younger pts) Differential ... #hematology #diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... initiation • Differential ... fluid overload, PCC ... diagnosis #management #hematology ... #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
immunophenotype Clinical ... Vmphocytosis on routine CBC ... chemotherapy for low-risk disease ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
activity - A low value ... hallmark for the disease ... If the value is ... count and differential ... Diagnosis #Workup #Hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
• Heavy Chain disease ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
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