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diagnosis ana antinuclear antibody cytoplasmic erythematosus lupus signs systemic testing workup agglutinin algorithm antibodies arthritis autoantibodies autoimmune behcet causes classification
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
: - SLE, SSc ... : - SjS, SLE, ... Rods/rings: - HCV ... #differential # ... diagnosis #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... erythematosus (SLE ... erythematosus (SLE ... #rheumatology # ... diagnosis #differential
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... pylori test (GI symptoms ... test, ANA (e.g., SLE ... anemia (vegan, ... Causes #Workup #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Drug-associated, PCH ... Defects: Sickle cell anemia ... #Diagnosis #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... - Hemolytic anemia ... • HCV, HBV Not ... #Diagnosis #hematology ... #rheumatology #
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
- Hemolytic anemia ... involvement 3% SLE-Related ... Lupusreference #SLE ... autoantibodies #signs #symptoms ... #rheumatology
Antinuclear Antibody Testing Cytoplasmic Patterns Reticular/AMA: • PBC, SSc, PBC/SSc OS, PBC/SjS OS • AMA Speckled: •
Testing Cytoplasmic Patterns ... Rods/rings: • HCV ... #Cytoplasmic #Patterns ... #differential # ... diagnosis #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
aseptic meningitis), MCC ... : Arterial (MCC-small ... ) Differential Diagnosis ... Oral aphthae : SLE ... #rheumatology #
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
of anemia include ... • hemolytic anemia ... younger pts) Differential ... #hemolytic #anemia ... #hematology #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Non-autoimmune rheumatologic ... lymphopenia, low PLT • Anemia ... Induced Lupus: • Symptoms ... Erythematosus #Diagnosis #Rheumatology
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